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❶Both cell types are of therapeutic interest as the increasing of clinical trials presented on www. Hollow fiber bioreactors in MSC expansion procedures Similarly to parallel plate bioreactors, hollow fiber bioreactors provide a low shear stress environment [ ] and cell propagation in continuous perfusion mode.

1. Introduction

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Shear stress is a force per unit area acting on and parallel to a surface. Table 1 gives an overview of commercially available microcarriers that are suitable in MSC expansions.

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